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KMID : 0384119870070020275
Korean Journal of Clinical Pathology
1987 Volume.7 No. 2 p.275 ~ p.281
Result of Peritoneal Dialysate Culture in Peritonitis Patients undergoing Continuous Ambulatory Peritoneall Dialysis



Abstract
Continuous ambulatory peritoneal dialysis(CAPD) is now considered an effective therapy for patients with end-stage renal disease. The most important and frequent complication of peritoneal dialysis is peritonitis.
Total 1,205 peritoneal dialysate specimens from 332 peritonitis patients during the period of January 1983 to June 1987 were gram-stained and cultured at Soonchunhyang University Hospital. ,
Laboratory data were analysed and the following results were obtained.
1) 246 specimens(20.4%) of the total 1,205 peritoneal dialysate specimens were culture positive and gram stains of peritoneal dialysate were positive in 23.4% of culture positive specimens.
2) Distribution of isolated organisms were gram-positive cocci 72.4%, gram-negative bacilli 22.0%, fungus 5.2% and Neisseria species 0.4%. Frequently isolated organisms in decreasing order were coagulase-negative Staphylococcus 35.8%, Staphylococcus
aureus 33.8%, Pseudomonas aeruginosa 8.4%, Acinetobacter calcoaceticus 4.0%,
Enterobacter 2.8% and E.coli 2.4%.
3) Polymicrobial infections were found in 1.7% of culture positive specimens.
4) Reinfection with same organisms were 16.1% of culture positive patients and reinfection with other organisms were 18.196 of culture positive patients.
5) Coagulase-negative Staphylococcus and Staphylococcus aureus revealed over 90
% sensitivity to Cefotaxime and Moxalactam but over 70% resistance to Kanamycin and Penicillin. Pseudomonas were highly susceptible to colistin(95%) but to Gentamicin (29%) less sensitive. Acinetobacter were highly susceptible to Amikacin, Gentamicin, Kanamycin and Tobramycin but highly resistant to Nitrofurantoin, Ampicillin, Cefo¡þtaxime and Moxalactam.
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